Controlled pilot study of the effects of neuromuscular therapy in patients with Parkinson's disease
Identifieur interne : 003513 ( Main/Exploration ); précédent : 003512; suivant : 003514Controlled pilot study of the effects of neuromuscular therapy in patients with Parkinson's disease
Auteurs : Lauren H. Craig [États-Unis] ; Anna Svircev [États-Unis] ; Michael Haber [États-Unis] ; Jorge L. Juncos [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-12.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
- Affect (physiology), Aged, Alternative medicine, Female, Human, Humans, Hypokinesia (etiology), Hypokinesia (therapy), Male, Massage, Middle Aged, Muscle Relaxation, Music, Music Therapy (methods), Nervous system diseases, Parkinson Disease (physiopathology), Parkinson Disease (psychology), Parkinson Disease (therapy), Parkinson disease, Parkinson's disease, Pilot Projects, Prospective Studies, Psychomotor Performance (physiology), Quality of Life, Questionnaires, Relaxation, Severity of Illness Index, Single-Blind Method, Time Factors, Treatment, Tremor (etiology), Tremor (therapy), complementary and alternative medicine, massage therapy, music relaxation, neuromuscular therapy.
- MESH :
- etiology : Hypokinesia, Tremor.
- methods : Music Therapy.
- physiology : Affect, Psychomotor Performance.
- physiopathology : Parkinson Disease.
- psychology : Parkinson Disease.
- therapy : Hypokinesia, Parkinson Disease, Tremor.
- Aged, Female, Humans, Male, Middle Aged, Muscle Relaxation, Pilot Projects, Prospective Studies, Quality of Life, Questionnaires, Severity of Illness Index, Single-Blind Method, Time Factors.
Abstract
The objectives of this study is to examine the effects of neuromuscular therapy (NMT) on motor and nonmotor symptoms in Parkinson's disease (PD). Thirty‐six subjects with PD were randomly assigned to NMT or music relaxation (MR, or active control). Subjects received treatment twice a week for 4 weeks. Testing was conducted at baseline, after final treatment, and 8 days after final treatment. Primary outcome measures were the Motor subscale of the United Parkinson Disease Rating Scale (UPDRS) and the Clinical Global Impression scale (CGI‐Change). Secondary outcome measures included a PD‐specific quality of life scale (PDQ‐39), quantitative measures of motor function, and severity scales for anxiety and depression symptoms. NMT resulted in a significant and sustained improvement in the Motor subscale of the UPDRS (P ≤ 0.0001), most notable in the tremor scores. Also improved 1 week after the last treatment were the CGI scores (P = 0.007) and the finger‐tapping speed (P = 0.001). The MR active control group had a slight improvement in tremor but evidenced no other change in motor function. Both groups exhibited a modest improvement in quality of life immediately after the last treatment. This effect was sustained for 8 days only in the MR group. In the nonmotor domains, the MR group evidenced improvements in mood (P = 0.001) and anxiety (P = 0.002), whereas NMT had no effect on mood (P = 0.09), and its initial effect on anxiety (P = 0.0009) dissipated after 8 days (P = 0.40). Group differences for UPDRS motor score and patient CGI‐Change were superior in the NMT compared to the MR group. There was no group difference in PDQ‐39 scores or in nonmotor measures. The findings suggest that NMT can improve motor and selected nonmotor symptoms in PD and that this effect is more durable for the motor symptoms. The results of this pilot study warrant larger controlled studies to examine dose range, durability, and mechanisms of NMT in PD function. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21132
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000584
- to stream Istex, to step Curation: 000584
- to stream Istex, to step Checkpoint: 001F73
- to stream PubMed, to step Corpus: 002A41
- to stream PubMed, to step Curation: 002A41
- to stream PubMed, to step Checkpoint: 002E02
- to stream Ncbi, to step Merge: 001898
- to stream Ncbi, to step Curation: 001898
- to stream Ncbi, to step Checkpoint: 001898
- to stream Main, to step Merge: 004827
- to stream PascalFrancis, to step Corpus: 001874
- to stream PascalFrancis, to step Curation: 001447
- to stream PascalFrancis, to step Checkpoint: 001B66
- to stream Main, to step Merge: 004C61
- to stream Main, to step Curation: 003513
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Controlled pilot study of the effects of neuromuscular therapy in patients with Parkinson's disease</title>
<author><name sortKey="Craig, Lauren H" sort="Craig, Lauren H" uniqKey="Craig L" first="Lauren H." last="Craig">Lauren H. Craig</name>
</author>
<author><name sortKey="Svircev, Anna" sort="Svircev, Anna" uniqKey="Svircev A" first="Anna" last="Svircev">Anna Svircev</name>
</author>
<author><name sortKey="Haber, Michael" sort="Haber, Michael" uniqKey="Haber M" first="Michael" last="Haber">Michael Haber</name>
</author>
<author><name sortKey="Juncos, Jorge L" sort="Juncos, Jorge L" uniqKey="Juncos J" first="Jorge L." last="Juncos">Jorge L. Juncos</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:C30074C8FAF92F5B21F30F2B2C4EFF41A3EFFFD5</idno>
<date when="2006" year="2006">2006</date>
<idno type="doi">10.1002/mds.21132</idno>
<idno type="url">https://api.istex.fr/document/C30074C8FAF92F5B21F30F2B2C4EFF41A3EFFFD5/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000584</idno>
<idno type="wicri:Area/Istex/Curation">000584</idno>
<idno type="wicri:Area/Istex/Checkpoint">001F73</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Craig L:controlled:pilot:study</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17044088</idno>
<idno type="wicri:Area/PubMed/Corpus">002A41</idno>
<idno type="wicri:Area/PubMed/Curation">002A41</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002E02</idno>
<idno type="wicri:Area/Ncbi/Merge">001898</idno>
<idno type="wicri:Area/Ncbi/Curation">001898</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001898</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Craig L:controlled:pilot:study</idno>
<idno type="wicri:Area/Main/Merge">004827</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:07-0090865</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001874</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001447</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001B66</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Craig L:controlled:pilot:study</idno>
<idno type="wicri:Area/Main/Merge">004C61</idno>
<idno type="wicri:Area/Main/Curation">003513</idno>
<idno type="wicri:Area/Main/Exploration">003513</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Controlled pilot study of the effects of neuromuscular therapy in patients with Parkinson's disease</title>
<author><name sortKey="Craig, Lauren H" sort="Craig, Lauren H" uniqKey="Craig L" first="Lauren H." last="Craig">Lauren H. Craig</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Atlanta School of Massage, Atlanta, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Svircev, Anna" sort="Svircev, Anna" uniqKey="Svircev A" first="Anna" last="Svircev">Anna Svircev</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Atlanta School of Massage, Atlanta, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Emory University, Rollins School of Public Health, Atlanta, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Haber, Michael" sort="Haber, Michael" uniqKey="Haber M" first="Michael" last="Haber">Michael Haber</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Emory University School of Public Health, Department of Biostatistics, Atlanta, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Juncos, Jorge L" sort="Juncos, Jorge L" uniqKey="Juncos J" first="Jorge L." last="Juncos">Jorge L. Juncos</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Emory University School of Medicine, Department of Neurology Movement Disorders Program, Atlanta, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2006-12">2006-12</date>
<biblScope unit="vol">21</biblScope>
<biblScope unit="issue">12</biblScope>
<biblScope unit="page" from="2127">2127</biblScope>
<biblScope unit="page" to="2133">2133</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">C30074C8FAF92F5B21F30F2B2C4EFF41A3EFFFD5</idno>
<idno type="DOI">10.1002/mds.21132</idno>
<idno type="ArticleID">MDS21132</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Affect (physiology)</term>
<term>Aged</term>
<term>Alternative medicine</term>
<term>Female</term>
<term>Human</term>
<term>Humans</term>
<term>Hypokinesia (etiology)</term>
<term>Hypokinesia (therapy)</term>
<term>Male</term>
<term>Massage</term>
<term>Middle Aged</term>
<term>Muscle Relaxation</term>
<term>Music</term>
<term>Music Therapy (methods)</term>
<term>Nervous system diseases</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (psychology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Pilot Projects</term>
<term>Prospective Studies</term>
<term>Psychomotor Performance (physiology)</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Relaxation</term>
<term>Severity of Illness Index</term>
<term>Single-Blind Method</term>
<term>Time Factors</term>
<term>Treatment</term>
<term>Tremor (etiology)</term>
<term>Tremor (therapy)</term>
<term>complementary and alternative medicine</term>
<term>massage therapy</term>
<term>music relaxation</term>
<term>neuromuscular therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypokinesia</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Music Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Affect</term>
<term>Psychomotor Performance</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Hypokinesia</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle Relaxation</term>
<term>Pilot Projects</term>
<term>Prospective Studies</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Severity of Illness Index</term>
<term>Single-Blind Method</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Homme</term>
<term>Massage</term>
<term>Musique</term>
<term>Médecine parallèle</term>
<term>Parkinson maladie</term>
<term>Relaxation</term>
<term>Système nerveux pathologie</term>
<term>Traitement</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
<term>Musique</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The objectives of this study is to examine the effects of neuromuscular therapy (NMT) on motor and nonmotor symptoms in Parkinson's disease (PD). Thirty‐six subjects with PD were randomly assigned to NMT or music relaxation (MR, or active control). Subjects received treatment twice a week for 4 weeks. Testing was conducted at baseline, after final treatment, and 8 days after final treatment. Primary outcome measures were the Motor subscale of the United Parkinson Disease Rating Scale (UPDRS) and the Clinical Global Impression scale (CGI‐Change). Secondary outcome measures included a PD‐specific quality of life scale (PDQ‐39), quantitative measures of motor function, and severity scales for anxiety and depression symptoms. NMT resulted in a significant and sustained improvement in the Motor subscale of the UPDRS (P ≤ 0.0001), most notable in the tremor scores. Also improved 1 week after the last treatment were the CGI scores (P = 0.007) and the finger‐tapping speed (P = 0.001). The MR active control group had a slight improvement in tremor but evidenced no other change in motor function. Both groups exhibited a modest improvement in quality of life immediately after the last treatment. This effect was sustained for 8 days only in the MR group. In the nonmotor domains, the MR group evidenced improvements in mood (P = 0.001) and anxiety (P = 0.002), whereas NMT had no effect on mood (P = 0.09), and its initial effect on anxiety (P = 0.0009) dissipated after 8 days (P = 0.40). Group differences for UPDRS motor score and patient CGI‐Change were superior in the NMT compared to the MR group. There was no group difference in PDQ‐39 scores or in nonmotor measures. The findings suggest that NMT can improve motor and selected nonmotor symptoms in PD and that this effect is more durable for the motor symptoms. The results of this pilot study warrant larger controlled studies to examine dose range, durability, and mechanisms of NMT in PD function. © 2006 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Géorgie (États-Unis)</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Craig, Lauren H" sort="Craig, Lauren H" uniqKey="Craig L" first="Lauren H." last="Craig">Lauren H. Craig</name>
</region>
<name sortKey="Haber, Michael" sort="Haber, Michael" uniqKey="Haber M" first="Michael" last="Haber">Michael Haber</name>
<name sortKey="Juncos, Jorge L" sort="Juncos, Jorge L" uniqKey="Juncos J" first="Jorge L." last="Juncos">Jorge L. Juncos</name>
<name sortKey="Svircev, Anna" sort="Svircev, Anna" uniqKey="Svircev A" first="Anna" last="Svircev">Anna Svircev</name>
<name sortKey="Svircev, Anna" sort="Svircev, Anna" uniqKey="Svircev A" first="Anna" last="Svircev">Anna Svircev</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003513 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003513 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:C30074C8FAF92F5B21F30F2B2C4EFF41A3EFFFD5 |texte= Controlled pilot study of the effects of neuromuscular therapy in patients with Parkinson's disease }}
This area was generated with Dilib version V0.6.23. |